ABSTRACT
Objective To analyze the epidemiological characteristics and risk factors of bronchial asthma (BA) complicated with recurrent respiratory tract infection (RRTI) in children in Hebei District, Tianjin City, and to provide a reference for the prevention and treatment of children with BA complicated with RRTI. Methods The stratified cluster sampling method was adopted to randomly select 428 children with BA hospitalized in Hebei District of Tianjin as the study subjects. The routine deep sputum culture and etiological examination were carried out. The children with RRTI were included in the experimental group (n=84), and the children without RRTI (n=344) were included in the control group. A self-designed questionnaire was used to investigate gender, age, smoking proportion of family members, use of antibiotics 3 times or more a year, and family history of allergy. The risk factors of BA combined with RRTI were analyzed by logistic regression. Results RRTI occurred in 84 of 428 children with BA, and the incidence rate was 19.63% (84/428). The proportion of BA complicated with RRTI in children aged 6 months to 2 years was higher than that in other age groups (χ2=6.213, P0.05). The proportion of family smoking, the use of antibiotics 3 times or more a year, and the proportion of family allergy history in the experimental group were significantly higher than those in the control group (P<0.05). Logistic regression analysis showed that family smoking, antibiotic use 3 times or more a year and family history of allergy were independent risk factors for BA complicated with RRTI (P<0.05). Conclusion The incidence of BA complicated with RRTI in children in Hebei District, Tianjin City is high, and the age of high incidence is 6 months to 2 years old. The proportion of family smoking, the use of antibiotics three times or more a year, and the proportion of family allergy history are the high-risk factors for the occurrence of BA complicated with RRTI in children in Hebei District, Tianjin City.